What is benign pleural mesothelioma ?

What is benign pleural mesothelioma

Pleural mesothelioma is a malignant tumour of the pleura (serous membrane of the lungs). The disease is primary, ie is not a metastasis of another tumour. Signs of the disease are: chest pain, shortness of breath, even with little effort or rest, prolonged dry cough, pleurisy, general exhaustion of the body. Pleural mesothelioma is characterized by high malignancy, rapidly developing and capable of metastasis. Without proper treatment, death occurs. You can use folk remedies to treat diseases. The treatment uses extracts from poisonous plants that at the right dose have a toxic effect on cancer cells, stopping the development of the tumour. It is also important to use medicines to strengthen your immune system and improve your overall health. This treatment will help the body fight the disease itself. Treatment with folk methods should be continuous and systematic, but only in this case can you get a permanent positive effect.

What is benign pleural mesothelioma

Causes of pathology

Pleural mesothelioma – a tumour of epithelial origin. The onset of malignant neoplasm is given by a single-layered squamous epithelium that the pleura leaves behind. The disease is much less common than lung cancer. Up to 20 cases per 1 million population have been registered, ie. the incidence is 0.002% of the total population. Most commonly, pleural mesothelioma is found in men over 50 years of age.

For mesothelioma, the causes of development are well established, which distinguishes this cancer process from most other cancers. In most cases, the development of this tumour is associated with prolonged human contact with asbestos. Such a disease develops in mine workers, asbestos industrial plants, as well as people living near plants producing and processing this substance. Mesothelioma develops several decades after contact with asbestos.

The development of the disease also depends on the type of asbestos. The size of asbestos fibers is important. Fibers with a length of 5–20 µm and a diameter of up to 1 µm are considered to be the greatest danger. Such fibers easily enter the lungs during respiration, penetrate the lymphatic system and settle into the subpleural space and tissues of the lungs. These fibers have a permanent toxic and mutagenic effect on the tissues and can cause various diseases, including pleural mesothelioma.

Asbestos

The worst part is that asbestos is now widely used in various industries. Often, employees of these businesses are not even aware that they are in contact with a dangerous substance that can cause cancer. Asbestos is used in the production of refractories, roofing materials, insulation, the automotive and many other industries. Contact with other toxic substances can provoke the formation of mesothelioma, although such cases are much less common. Carcinogens include heavy metals (copper, nickel, beryllium), liquid paraffin and others. Increases the likelihood of developing mesothelioma and smoking, although this habit does not in itself lead to the onset of the disease (but may provoke other oncological processes).

In rare cases, mesothelioma can develop against radiation therapy for another cancer. The irradiation causes damage to the DNA structure of the pleural cells and they begin to divide uncontrollably, forming a tumour. However, mesothelioma is not a metastasis of the primary tumour. There is a potential for genetic predisposition to cancer, including mesothelioma. Also, the likelihood of developing the disease is higher in people who carry the SV-40 virus. All these factors can increase the likelihood of pleural cancer, but in most cases it causes contact with toxic substances, most often asbestos.

Development of tumours

In the initial stage of pleural neoplasm, small nodes are formed. Depending on the type of tumour, two types of mesothelioma are distinguished: a nodular form in which the nodes merge into a dense node and a diffuse form in which the tumour spreads and surrounds the pleura. With the development of the tumour, a serous-fibrinous or hemorrhagic exudate is formed in the pleural cavity. In the later stages, the tumour grows in the lungs, diaphragm and intercostal muscles and forms lymph node metastases. The spread of metastases occurs in the lymphatic system.

As for other cancers, there are 4 stages of mesothelioma development:

  • The tumour affects only the parietal leaf of the pleura.
  • Neoplasm grows in the visceral leaflet, and the diaphragm, intercostal muscles and lung tissue may be affected on one side.
  • The tumour spreads to other tissues of the chest and nearby lymph nodes.
  • Neoplasm affects bone tissue (ribs and spine), distant metastases are formed.

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